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The BIOFIRE System and Your Immune System The BIOFIRE System provides syndromic infectious disease testing, empowering healthcare providers to select the appropriate test the first time. Patients benefit from faster diagnoses and more targeted treatment. Clinicians benefit from improved stewardship of antibiotics. Labs improve efficiency and cost savings. The BioFire Pneumonia Plus Panel (PN panel) tests native sputum (including mini-BAL) as well as endotracheal sludge and bronchoalveolar liquids (including mini BAL) for 33 clinically important pathogens and resistance genes to antimicrobials in an hour. Respiratory The burning of biomass (wood, plants and other organic materials) produces gaseous pollutants and fine particles of matter that adversely affect the respiratory system. Furthermore, the environmental issues caused by forest fires, like droughts, could be exacerbated by climate change, which can increase their negative impact on human health. In the United States, wildfire smoke has been linked to hospitalizations for respiratory diseases, such as asthma, COPD and lung cancer. Furthermore, this type of air pollution is an underlying risk factor for cardiovascular diseases and a major contributing factor to the burden of illness for the most vulnerable population, including people with lower socioeconomic status (SES). During the COVID-19 pandemic, a number of communities were exposed to harmful levels of air pollution resulting from wildfires. However the public health response to this environmental problem is sporadic and mainly focused on communicating regarding symptom management. This knowledge gap is troubling given the evidence of potential health risks resulting from the continual exposure to smoke and other causes of poor air quality. Researchers are now looking at the best methods to safeguard public health during future events similar to this. NIH is funding research on this critical public health problem through the BLUE CORAL study and its successor FIRE CORAL. For the first time, a prospective cohort study will assess long-term outcomes from exposure to smoke from wildfires and other sources. FIRE CORAL is recruiting adult participants who have been hospitalized for COVID-19's index episode who are fluent in English or Spanish and are not pregnant. The protocol for FIRE CORAL includes a set of tests in-person that objectively measure the pulmonary function test and lung imaging and functional assessment. Smoke and other particles can cause or worsen respiratory conditions such as emphysema, COPD and pneumonia. A number of steps can be taken to prevent or minimize the negative health effects from short-term exposures to smoke, including avoidance of outdoor activities whenever feasible and wearing the EPA's “N95” mask, which is designed to trap fine particles. Smoking can cause irritation to the throat, eyes and nose. To help reduce symptoms, drink lots of water and take medication to reduce inflammation, like corticosteroids. Bloodstream Your bloodstream is on the front lines of fighting germs that invade your body. Dendritic cells are specific cells, serve as a call center for your fire department. They collect antigens from germs and release proteins that signal other white cells to fight off them. The white blood cell counts, differentials and band cells were elevated following firefighters' fire-fighting shifts, as compared to levels following strenuous physical exercise without fire-fighting. Skin As the wildfires in California released smoke and dust into the air over the course of autumn and winter, dermatologists were concerned about how that could affect the skin of those who were exposed to it. Maria Wei, a graduate student at University of California, Irvine is researching how extreme wildfire pollution affects the skin. Her research was published in Scientific Reports on April 22. Fireplaces And Stove shows that the temperature of the skin changes based on the length of time that the body is exposed to flames. It takes upwards of two hours for a person's skin to reach its flash point—the temperature at which it starts to burn and then turns into a ashy. This is the reason why it's essential to stay away from an open flame or campfire and why you should wear protective clothing when you are outside during a forest fire or even an extremely hot day. While it's essential to take precautions against wildfire pollution, there is no way to stop forest fires from occurring. Wei is predicting that the number of people suffering the consequences of wildfires will increase as climate change causes more forests to burn. This means that more people will need to wear caps and long sleeves as well as thick moisturizers. Air pollution from wildfires can exacerbate atopic skin dermatitis, which causes itchy skin in a lot of people. She says that the particles in smoke can clog up pores, making atopic skin worse. Atopic dermatitis may also make people more sensitive towards UV light. This is often exacerbated by smoke from wildfires. This can result in people looking for tanning salons and get tanned with less protection. While a fire and ice facial may reduce the effects of atopic dermatitis it's not recommended for anyone who has an open wound or rash on their face. This treatment is not recommended for those with active acne or if you're pregnant or nursing. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' most prestigious membership MedSpa It's a highly effective and effective facial that bridges the gap between a light facial and a peel, without having to wait for any downtime. It's designed to smooth the skin, alleviate the appearance of rosacea, reduce acne scarring, reduce lines and wrinkles, and stimulate the renewal of cells. This is a fantastic treatment to provide your skin with a radiant glow. Infections The human body is made up of a complex system of organs and tissues which work together to guard against infection. Infections are caused by microscopic organisms like parasites, viruses, bacteria and fungus that invade healthy cells and cause them to multiply beyond control. If this occurs your immune system can react with symptoms of illness. These symptoms could include a runny nose to an upset stomach and can also include a fever, swollen lymph glands or a rash. The nature of the infection and its location can affect the severity of your symptoms. Infections spread in many ways, but the most common are from person to person through droplets that linger in the air after coughing or sneezing. Bacterial diseases such as strep throat, tuberculosis, meningococcal disease and Legionnaires' disease spread in this manner, as do some viral infections, such as the common cold and influenza. Certain infections caused by bacteria, such as skin infections and sexually transmitted diseases (STIs) like gonorrhea and Chlamydia, can be transmitted through direct contact with infected tissues or mucous membranes as well as indirect contact with surfaces that are contaminated. Some bacterial diseases are transmitted by insects like ticks, mosquitoes or fleas, and are transmitted when they bite you. Viruses, parasites and other microorganisms are tiny enough to be able to get into the bloodstream and cause infection to your cells. This can lead to serious diseases like the common cold or AIDS. Fungi are responsible for a myriad of skin conditions such as ringworm, athlete's foot, while some affect the lungs or the nervous system, like the rabies virus. The BioFire Panel uses our innovative FilmArray technology to analyze the sputum and bronchoalveolar fluid samples to determine a comprehensive list of pathogens that are involved in upper respiratory infection. The kit comes with a reagent kit that contains all the chemistry needed to perform reverse transcription, nested multiplex PCR, and detection with a single machine. This is a straightforward solution that helps clinicians identify and treat patients with various respiratory symptoms. This test has been issued an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high complexity laboratories.